I just got started with blogs this year and I can say that at first I ONLY signed up with sponsors that used CCBill. It was just too easy to amass a huge number of sponsors this way that gave me access to tons of content for my blogs. I also liked the fact that I didn't have to send out my personal details to a bunch of other sites.

But then after 6 months I started to sign up for Epoch programs and finally the custom ones run by the mega sites.

But if I was starting out with a pay site I'd definitely use CCBill because of the ease of use for affiliate sign-ups.