Coda (coding IDE with integrated sFTP)
Adium (multi protocoll messenger)
Safari 4 (webkit engine)

running when needet: Opera and Firefox (pronto and gecko engine), Photoshop cs4, Thunderbird.

Mostly I have the three browsers for their different engines: since IE is not avail for Mac (which I think is not a loss in this really awesome user experience world now) and Chrome is not avail yet its just those three.

*looks into the Dock*

no, not much more needet here in my little world