Do you mean use them as a publisher (affiliate webmaster) or as an advertiser (sponsor to sell your products)?

If you are talking about using them as an advertiser, i would say no, there are much better affiliate networks out there such as http://www.darkblue.com or http://www.linkshare.com

If you are talking about using them as a publisher, as long as you arent trying to be both 'adult' and 'non-adult' on the same site, (as another company tried to do recently and got canned by them LOL) then id say yes, they dont have the highest payouts on some of their products but, they have a lot of products so you should be able to find at least one that will work for your traffic base

Regards,

Lee