Current, I would say Drawn Together. Can I have a mention for Wonder Showzen? it's got animation and live action. Imagine Sesame Street on some really bad acid.

As far as classic cartoons, definitely Warner Bros., Scooby Doo, Rocky & Bullwinkle and the original Spiderman (which often gave me nightmares as a kid). And Patti, yes I remember Gulliver's Travels. It was part of the Banana Splits Show along with the adventures of Tom and Huck, where they were real life but existed on a cartoon world, kind of like Rodger Rabbit on much, much creepier.